The Gut–Lung Axis in Asthma: How Gut Microbes and Diet Interact
by Anna Sandhu | Jun 26, 2025
Reviewed by Dr. Arun, M.Pharm., PGDRA, Ph.D.
Asthma is a condition where your lungs are sensitive and can react to things like allergens, pollution or diet. Scientists now believe there is a strong connection between your gut (where lots of microbes live) and your lungs. This link is called the gut-lung axis. The recent review study explored how different dietary patterns (what you eat) affect your gut bacteria, and how that in turn may influence asthma.
Here’s the story:
Your gut is filled with trillions of microbes that help digest food, produce helpful compounds, and shape your immune system. When the gut microbiota is out of balance, it may lead to more inflammation and weaker immune responses. Meanwhile, your lungs depend on a healthy immune system too. The gut-lung axis means that changes in the gut can send signals to the lungs and affect lung health.
The review found that diet plays a big role. A diet like the Mediterranean diet (lots of veggies, fruits, legumes, whole grains, healthy fats) supports more diverse, healthier gut bacteria and produces anti-inflammatory compounds. That helps immune balance and may ease asthma risk or severity. On the other hand, a typical Western diet (high in processed foods, sugar, saturated fat, low in fiber) can hurt gut bacteria diversity, increase pro-inflammatory compounds, and may make asthma worse.
The review also described how gut microbe products (like short-chain fatty acids, SCFAs) and bacterial components (like lipopolysaccharides) travel through the body and can influence lung inflammation or immune cells in the lungs. So, what happens in the gut doesn’t stay in the gut. It can reach the lungs.
What does this mean for you or someone dealing with asthma? It suggests that part of managing lung health (and asthma) may involve supporting gut health through diet. Eating more fiber, more plant-rich foods, less processed foods may help your gut microbiome and in turn your lungs. It is NOT a guaranteed fix for asthma, but it adds a smart, diet-based piece to the treatment puzzle.
In short: Your gut and your lungs are connected. Your diet influences your gut microbes which influence your immune system and lungs. Choosing a gut-friendly diet may be another way to support better lung health and more balanced immune responses.
More Information: Gut-lung Axis mediates asthma pathogenesis: Roles of dietary patterns and their impact on the gut microbiota. DOI: https://doi.org/10.1016/j.yexmp.2025.104964